What cannabinoid drug is often prescribed for chemotherapy-induced nausea and vomiting when other antiemetics have failed?

Study Pharmacology Antiemetic Agents. Use flashcards and multiple choice questions with hints and explanations. Prepare for success!

Dronabinol is the correct answer as it is a synthetic form of tetrahydrocannabinol (THC), the active ingredient in cannabis, specifically approved for treating nausea and vomiting associated with chemotherapy when other antiemetic medications have not been effective. Dronabinol works by acting on cannabinoid receptors in the central nervous system, which helps to mediate the sensations of nausea and vomiting.

Marinol, while it refers to the brand name for dronabinol, is not as specific as simply stating the active pharmaceutical ingredient. Therefore, identifying dronabinol directly allows for a clearer understanding of the medication used.

Nabilone is another cannabinoid that can also be used for similar indications; however, it is not as commonly the first choice as dronabinol. Lastly, Sativex is primarily used for the treatment of neuropathic pain and spasticity associated with multiple sclerosis, rather than for chemotherapy-related nausea and vomiting, making it unsuitable in this context.

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