What adverse effect should the nurse monitor for in clients receiving phenothiazines like promethazine?

The choice of sedation as the adverse effect to monitor for in clients receiving phenothiazines like promethazine is grounded in the pharmacological action of these medications. Phenothiazines are primarily used for their antipsychotic and antiemetic properties, and they work by blocking dopamine receptors in the brain. This mechanism can produce a calming effect, which often results in sedation as a common side effect.

Patients taking promethazine may experience varying degrees of sedation, ranging from mild drowsiness to significant lethargy. It's essential for nurses to assess the patient's level of alertness and respond appropriately to prevent falls or injuries, especially in older adults or those who may be taking other sedative medications concurrently.

Other potential adverse effects of phenothiazines, while important to be aware of, do not occur as frequently as sedation. For instance, weight gain may occur but is typically associated with longer-term use of certain antipsychotic medications rather than acute treatment with promethazine. Bone marrow suppression is less common and would not be a primary concern with phenothiazines like promethazine. Lastly, insomnia is generally not a common side effect, as these medications are more likely to induce sleep than disturb it. Therefore, monitoring for