How does metoclopramide promote gastric emptying?

Study Pharmacology Antiemetic Agents. Use flashcards and multiple choice questions with hints and explanations. Prepare for success!

Metoclopramide promotes gastric emptying primarily by increasing gastric contractions. This medication acts as a prokinetic agent, meaning it enhances the movement of the gastrointestinal tract. Specifically, metoclopramide stimulates the smooth muscle of the stomach to contract more forcefully and more frequently, which helps to propel gastric contents into the small intestine more efficiently.

This action is particularly beneficial for patients experiencing delayed gastric emptying, as it improves coordination between the stomach and the intestines, facilitating quicker and more effective digestion. Overall, the enhancement of gastric peristalsis directly contributes to the acceleration of gastric emptying.

In contrast, the other options do not accurately describe the primary mechanism by which metoclopramide operates. Decreasing stomach acid does not directly influence the pace of gastric emptying; relaxing the esophagus pertains more to the movement of food into the stomach rather than the emptying from it, and slowing down digestion is contrary to the intended effect of metoclopramide as it is designed to aid digestion rather than hinder it.

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